Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation 106, 3143–3421 (2002).
Aryan, Z. et al. The prevalence, awareness, and treatment of lipid abnormalities in Iranian adults: Surveillance of risk factors of noncommunicable diseases in Iran 2016. J. Clin. Lipidol. 12, 1471-1481.e1474. https://doi.org/10.1016/j.jacl.2018.08.001 (2018).
World Health Organization. Quantifying selected major risks to health. The World Health Report 2002; Reducing risks, promoting healthy life (World Health Organization, 2002).
Haskell, W. L. Cardiovascular disease prevention and lifestyle interventions: Effectiveness and efficacy. J. Cardiovasc. Nurs. 18, 245–255. https://doi.org/10.1097/00005082-200309000-00003 (2003).
Song, S. J., Paik, H. Y., Park, M. & Song, Y. J. Dyslipidemia patterns are differentially associated with dietary factors. Clin. Nutr. 35, 885–891. https://doi.org/10.1016/j.clnu.2015.06.002 (2016).
Barry, M. P. et al. Towards unified and impactful policies to reduce ultra-processed food consumption and promote healthier eating. Lancet Diabetes Endocrinol. 9, 462–470. https://doi.org/10.1016/S2213-8587(21)00078-4 (2021).
Ebner, P., Frank, K., Christodoulou, A. & Davidou, S. How are the processing and nutrient dimensions of foods interconnected? An issue of hierarchy based on three different food scores. Int. J. Food Sci. Nutr. 73, 770–785 (2022).
Monteiro, C. A. et al. Ultra-processed foods: What they are and how to identify them. Public Health Nutr. 22, 936–941. https://doi.org/10.1017/S1368980018003762 (2019).
Cordova, R. et al. Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study. Clin. Nutr. 40, 5079–5088 (2021).
Donat-Vargas, C. et al. High consumption of ultra-processed food is associated with incident dyslipidemia: A prospective study of older adults. J. Nutr. 151, 2390–2398. https://doi.org/10.1093/jn/nxab118 (2021).
Lima, L. R. et al. Association between ultra-processed food consumption and lipid parameters among adolescents. Cien Saude Colet 25, 4055–4064. https://doi.org/10.1590/1413-812320202510.24822018 (2020).
Pagliai, G. et al. Consumption of ultra-processed foods and health status: A systematic review and meta-analysis. Br. J. Nutr. 125, 308–318. https://doi.org/10.1017/s0007114520002688 (2021).
Ochoa-Avilés, A. et al. Dietary intake practices associated with cardiovascular risk in urban and rural Ecuadorian adolescents: A cross-sectional study. BMC Public Health 14, 939. https://doi.org/10.1186/1471-2458-14-939 (2014).
Rauber, F., Campagnolo, P. D., Hoffman, D. J. & Vitolo, M. R. Consumption of ultra-processed food products and its effects on children’s lipid profiles: A longitudinal study. Nutr. Metab. Cardiovasc. Dis. 25, 116–122. https://doi.org/10.1016/j.numecd.2014.08.001 (2015).
Kohansal, A. et al. Association between plant and animal proteins intake with lipid profile and anthropometric indices: A cross-sectional study. Nutr. Health https://doi.org/10.1177/02601060221104311 (2022).
Borazjani, M., Nouri, M., Venkatakrishnane, K., Najafi, M. & Faghih, S. Association of plant-based diets with lipid profile and anthropometric indices: A cross-sectional study. Nutr. Food Sci. 52, 830–842 (2022).
Mirmiran, P., Esfahani, F. H., Mehrabi, Y., Hedayati, M. & Azizi, F. Reliability and relative validity of an FFQ for nutrients in the Tehran lipid and glucose study. Public Health Nutr. 13, 654–662. https://doi.org/10.1017/s1368980009991698 (2010).
Monteiro, C. A. et al. The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing. Public Health Nutr. 21, 5–17. https://doi.org/10.1017/s1368980017000234 (2018).
Jafari, F. et al. Ultra-processed food intake and risk of colorectal cancer: A matched case-control study. Nutr. Cancer 75, 532–541. https://doi.org/10.1080/01635581.2022.2125990 (2023).
Biernat, E., Stupnicki, R., Lebiedziński, B. & Janczewska, L. Assessment of physical activity by applying IPAQ questionnaire. Phys. Educ. Sport 52, 46–52. https://doi.org/10.2478/v10030-008-0019-1 (2008).
Salcedo-Cifuentes, M., Belalcazar, S., Acosta, E. Y. & Medina-Murillo, J. J. Conventional biomarkers for cardiovascular risks and their correlation with the Castelli Risk Index-Indices and TG/HDL-C. Archivos de Medicina (Manizales) 20, 11–22 (2020).
Huang, P. L. A comprehensive definition for metabolic syndrome. Dis. Model. Mech. 2, 231–237. https://doi.org/10.1242/dmm.001180 (2009).
Wongcharoen, W., Sutthiwutthichai, S., Gunaparn, S. & Phrommintikul, A. Is non-HDL-cholesterol a better predictor of long-term outcome in patients after acute myocardial infarction compared to LDL-cholesterol? A retrospective study. BMC Cardiovasc. Disord. 17, 10. https://doi.org/10.1186/s12872-016-0450-9 (2017).
Lotfi, M. et al. Plant-based diets could ameliorate the risk factors of cardiovascular diseases in adults with chronic diseases. Food Sci. Nutr. 11, 1297–1308 (2022).
Lima, L. R. et al. Association between ultra-processed food consumption and lipid parameters among adolescents. Ciência Saúde Coletiva 25, 4055–4064 (2020).
Beslay, M. et al. Ultra-processed food intake in association with BMI change and risk of overweight and obesity: A prospective analysis of the French NutriNet-Santé cohort. PLoS Med. 17, e1003256. https://doi.org/10.1371/journal.pmed.1003256 (2020).
Li, M. & Shi, Z. Ultra-processed food consumption associated with overweight/obesity among Chinese adults—Results from China Health and Nutrition Survey 1997–2011. Nutrients 13, 2796 (2021).
Mendonça, R. D. et al. Ultra-processed food consumption and the incidence of hypertension in a Mediterranean cohort: The Seguimiento Universidad de Navarra Project. Am. J. Hypertens. 30, 358–366 (2017).
Konieczna, J. et al. Contribution of ultra-processed foods in visceral fat deposition and other adiposity indicators: Prospective analysis nested in the PREDIMED-Plus trial. Clin. Nutr. 40, 4290–4300 (2021).
Sandoval-Insausti, H. et al. Ultra-processed food consumption is associated with abdominal obesity: A prospective cohort study in older adults. Nutrients 12, 2368 (2020).
Cordova, R. et al. Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study. Clin. Nutr. (Edinburgh, Scotland) 40, 5079–5088. https://doi.org/10.1016/j.clnu.2021.08.009 (2021).
Mehta, K. et al. Marketing foods to children through product packaging: Prolific, unhealthy and misleading. Public Health Nutr. 15, 1763–1770 (2012).
de Graaf, C. J. A. Effects of snacks on energy intake: An evolutionary perspective. Appetite 47, 18–23 (2006).
Garber, A. K. & Lustig, R. H. Is fast food addictive?. Curr. Drug Abuse Rev. 4, 146–162 (2011).
Lissner, L. et al. Television habits in relation to overweight, diet and taste preferences in European children: The IDEFICS study. Eur. J. Epidemiol. 27, 705–715 (2012).
Parks, E. J., Skokan, L. E., Timlin, M. T. & Dingfelder, C. S. Dietary sugars stimulate fatty acid synthesis in adults. J. Nutr. 138, 1039–1046 (2008).
Chong, M. F., Fielding, B. A. & Frayn, K. N. Mechanisms for the acute effect of fructose on postprandial lipemia. Am. J. Clin. Nutr. 85, 1511–1520 (2007).
Astrup, A. et al. Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC state-of-the-art review. J. Am. Coll. Cardiol. 76, 844–857 (2020).
Seok, Y. J. et al. Furan in thermally processed foods—A review. Toxicol. Res. 31, 241–253. https://doi.org/10.5487/tr.2015.31.3.241 (2015).
Milošević, N. et al. Could phthalates exposure contribute to the development of metabolic syndrome and liver disease in humans?. Environ. Sci. Pollut. Res. 27, 772–784. https://doi.org/10.1007/s11356-019-06831-2 (2020).
Golestanzadeh, M., Riahi, R. & Kelishadi, R. Association of exposure to phthalates with cardiometabolic risk factors in children and adolescents: A systematic review and meta-analysis. Environ. Sci. Pollut. Res. 26, 35670–35686. https://doi.org/10.1007/s11356-019-06589-7 (2019).
Srour, B. & Touvier, M. Ultra-processed foods and human health: What do we already know and what will further research tell us?. EClinicalMedicine 32, 100747. https://doi.org/10.1016/j.eclinm.2021.100747 (2021).
Milošević, N. et al. Could phthalates exposure contribute to the development of metabolic syndrome and liver disease in humans?. Environ. Sci. Pollut. Res. Int. 27, 772–784. https://doi.org/10.1007/s11356-019-06831-2 (2020).
Hollænder, P. L., Ross, A. B. & Kristensen, M. Whole-grain and blood lipid changes in apparently healthy adults: A systematic review and meta-analysis of randomized controlled studies. Am. J. Clin. Nutr. 102, 556–572 (2015).
Juul, F., Vaidean, G. & Parekh, N. Ultra-processed foods and cardiovascular diseases: Potential mechanisms of action. Adv. Nutr. (Bethesda, MD) 12, 1673–1680. https://doi.org/10.1093/advances/nmab049 (2021).