Wednesday, September 27, 2023
BestWooCommerceThemeBuilttoBoostSales-728x90

Systemic adiponectin levels in colorectal cancer and adenoma: a systematic review and meta-analysis – International Journal of Obesity


  • Hanyuda A, Lee DH, Ogino S, Wu K, Giovannucci EL. Long-term status of predicted body fat percentage, body mass index and other anthropometric factors with risk of colorectal carcinoma: Two large prospective cohort studies in the US. Int J Cancer. 2020;146:2383–93.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Bardou M, Barkun AN, Martel M. Obesity and colorectal cancer. Gut. 2013;62:933–47.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer. 2004;4:579–91.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Pu X, Chen D. Targeting adipokines in obesity-related tumors. Front Oncol. 2021;11:685923.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Scheurlen KM, Chariker JH, Kanaan Z, Littlefield AB, George JB, Seraphine C, et al. The NOTCH4-GATA4-IRG1 axis as a novel target in early-onset colorectal cancer. Cytokine Growth Factor Rev. 2022;67:25–34.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • van Kruijsdijk RC, van der Wall E, Visseren FL. Obesity and cancer: the role of dysfunctional adipose tissue. Cancer Epidemiol Biomarkers Prev. 2009;18:2569–78.

    Article 
    PubMed 

    Google Scholar
     

  • Chakraborty D, Jin W, Wang J. The bifurcated role of adiponectin in colorectal cancer. Life Sci. 2021;278:119524.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wei T, Ye P, Peng X, Wu LL, Yu GY. Circulating adiponectin levels in various malignancies: an updated meta-analysis of 107 studies. Oncotarget. 2016;7:48671–91.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Luo Y, Liu M. Adiponectin: a versatile player of innate immunity. J Mol Cell Biol. 2016;8:120–8.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Olecki EJ, Perez Hoguin RA, King S, Razavi N, Scow JS. High-grade dysplasia in inflammatory bowel disease: indication for colectomy. Dis Colon Rectum. 2023;66:262–8.

    Article 
    PubMed 

    Google Scholar
     

  • Olén O, Erichsen R, Sachs MC, Pedersen L, Halfvarson J, Askling J, et al. Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study. Lancet. 2020;395:123–31.

    Article 
    PubMed 

    Google Scholar
     

  • Yoon YS, Kwon AR, Lee YK, Oh SW. Circulating adipokines and risk of obesity related cancers: a systematic review and meta-analysis. Obes Res Clin Pract. 2019;13:329–39.

    Article 
    PubMed 

    Google Scholar
     

  • Ogunwobi OO, Beales IL. Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regul Pept. 2006;134:105–13.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Cai L, Xu S, Piao C, Qiu S, Li H, Du J. Adiponectin induces CXCL1 secretion from cancer cells and promotes tumor angiogenesis by inducing stromal fibroblast senescence. Mol Carcinog. 2016;55:1796–806.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ferroni P, Palmirotta R, Spila A, Martini F, Raparelli V, Fossile E, et al. Prognostic significance of adiponectin levels in non-metastatic colorectal cancer. Anticancer Res. 2007;27:483–9.

    CAS 
    PubMed 

    Google Scholar
     

  • Lukanova A, Söderberg S, Kaaks R, Jellum E, Stattin P. Serum adiponectin is not associated with risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2006;15:401–2.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zekri AR, Bakr YM, Ezzat MM, Zakaria MS, Elbaz TM. Circulating levels of adipocytokines as potential biomarkers for early detection of colorectal carcinoma in Egyptian patients. Asian Pac J Cancer Prev. 2015;16:6923–8.

    Article 
    PubMed 

    Google Scholar
     

  • Tao WJ, Artama M, von Euler-Chelpin M, Hull M, Ljung R, Lynge E, et al. Colon and rectal cancer risk after bariatric surgery in a multicountry Nordic cohort study. Int J Cancer. 2020;147:728–35.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Mackenzie H, Markar SR, Askari A, Faiz O, Hull M, Purkayastha S, et al. Obesity surgery and risk of cancer. Br J Surg. 2018;105:1650–7.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Derogar M, Hull MA, Kant P, Östlund M, Lu Y, Lagergren J. Increased risk of colorectal cancer after obesity surgery. Ann Surg. 2013;258:983–8.

    Article 
    PubMed 

    Google Scholar
     

  • Clapp B, Portela R, Sharma I, Nakanishi H, Marrero K, Schauer P, et al. Risk of non-hormonal cancer after bariatric surgery: meta-analysis of retrospective observational studies. Br J Surg. 2022;110:24–33.

    Article 
    PubMed 

    Google Scholar
     

  • Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Bmj. 2021;372:n71.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Macleod, A, Scheurlen KS, Burton J, Parks MA, Galandiuk S. A systematic review and meta-analysis of the association between plasma adiponectin levels and colorectal cancer. PROSPERO 2022 CRD42022303307. 2022. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=303307.

  • Wells GA, Shea B, O’Connell D, Peterson J, Welch V, Losos M, Tugwell P. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2021. Available from: https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp.

  • McGrath S, Zhao X, Steele R, Thombs BD, Benedetti A. DEPRESsion Screening Data (DEPRESSD) Collaboration. Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis. Stat Methods Med Res. 2020;29:2520–37. Epub 30 Jan 2020.

  • Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014;14:135.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Taylor KS, Mahtani KR, Aronson JK. Combining and converting groups when extracting data for meta-analysis. BMJ Evid Based Med. 2021;26:85–7.

    Article 
    PubMed 

    Google Scholar
     

  • Human Development Index 2023. Updated June 2023. Available from: https://hdr.undp.org/data-center/human-development-index#/indicies/HDI.

  • Viechtbauer W, Cheung MW. Outlier and influence diagnostics for meta-analysis. Res Synth Methods. 2010;1:112–25.

    Article 
    PubMed 

    Google Scholar
     

  • R Core Team (2022). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. 2022. Available from: https://www.R-project.org/.

  • Harrer M, Cuijpers P, Furukawa TA, Ebert DD. Doing meta-analysis with R: a hands-on guide. In: Boca Raton, FL, editor. 1st ed. London: Chapman & Hall/CRC Press; 2021.

  • Wei EK, Giovannucci E, Fuchs CS, Willett WC, Mantzoros CS. Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. J Natl Cancer Inst. 2005;97:1688–94.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Stocks T, Lukanova A, Johansson M, Rinaldi S, Palmqvist R, Hallmans G, et al. Components of the metabolic syndrome and colorectal cancer risk; a prospective study. Int J Obes (Lond). 2008;32:304–14.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kumor A, Daniel P, Pietruczuk M, Małecka-Panas E. Serum leptin, adiponectin, and resistin concentration in colorectal adenoma and carcinoma (CC) patients. Int J Colorectal Dis. 2009;24:275–81.

    Article 
    PubMed 

    Google Scholar
     

  • Guadagni F, Roselli M, Martini F, Spila A, Riondino S, D’Alessandro R, et al. Prognostic significance of serum adipokine levels in colorectal cancer patients. Anticancer Res. 2009;29:3321–7.

    CAS 
    PubMed 

    Google Scholar
     

  • Erarslan E, Turkay C, Koktener A, Koca C, Uz B, Bavbek N. Association of visceral fat accumulation and adiponectin levels with colorectal neoplasia. Dig Dis Sci. 2009;54:862–8.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Nakajima TE, Yamada Y, Hamano T, Furuta K, Matsuda T, Fujita S, et al. Adipocytokines as new promising markers of colorectal tumors: adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer. Cancer Sci. 2010;101:1286–91.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kemik O, Sumer A, Kemik AS, Hasirci I, Purisa S, Dulger AC, et al. The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. World J Surg Oncol. 2010;8:85.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gonullu G, Kahraman H, Bedir A, Bektas A, Yücel I. Association between adiponectin, resistin, insulin resistance, and colorectal tumors. Int J Colorectal Dis. 2010;25:205–12.

    Article 
    PubMed 

    Google Scholar
     

  • Svobodova S, Topolcan O, Holubec L Jr, Levy M, Pecen L, Svacina S. Parameters of biological activity in colorectal cancer. Anticancer Res. 2011;31:373–8.

    CAS 
    PubMed 

    Google Scholar
     

  • Gialamas SP, Petridou ET, Tseleni-Balafouta S, Spyridopoulos TN, Matsoukis IL, Kondi-Pafiti A, et al. Serum adiponectin levels and tissue expression of adiponectin receptors are associated with risk, stage, and grade of colorectal cancer. Metabolism. 2011;60:1530–8.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Al Khaldi RM, Al Mulla F, Al Awadhi S, Kapila K, Mojiminiyi OA. Associations of single nucleotide polymorphisms in the adiponectin gene with adiponectin levels and cardio-metabolic risk factors in patients with cancer. Dis Markers. 2011;30:197–212.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Catalán V, Gómez-Ambrosi J, Rodríguez A, Ramírez B, Silva C, Rotellar F, et al. Up-regulation of the novel proinflammatory adipokines lipocalin-2, chitinase-3 like-1 and osteopontin as well as angiogenic-related factors in visceral adipose tissue of patients with colon cancer. J Nutr Biochem. 2011;22:634–41.

    Article 
    PubMed 

    Google Scholar
     

  • Touvier M, Fezeu L, Ahluwalia N, Julia C, Charnaux N, Sutton A, et al. Pre-diagnostic levels of adiponectin and soluble vascular cell adhesion molecule-1 are associated with colorectal cancer risk. World J Gastroenterol. 2012;18:2805–12.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kemik O, Kemik AS, Begenik H, Erdur FM, Emre H, Sumer A, et al. The relationship among acute-phase responce proteins, cytokines, and hormones in various gastrointestinal cancer types patients with cachectic. Hum Exp Toxicol. 2012;31:117–25.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ho GY, Wang T, Gunter MJ, Strickler HD, Cushman M, Kaplan RC, et al. Adipokines linking obesity with colorectal cancer risk in postmenopausal women. Cancer Res. 2012;72:3029–37.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hillenbrand A, Fassler J, Huber N, Xu P, Henne-Bruns D, Templin M, et al. Changed adipocytokine concentrations in colorectal tumor patients and morbidly obese patients compared to healthy controls. BMC Cancer. 2012;12:545.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gulcelik MA, Colakoglu K, Dincer H, Dogan L, Yenidogan E, Gulcelik NE. Associations between adiponectin and two different cancers: breast and colon. Asian Pac J Cancer Prev. 2012;13:395–8.

    Article 
    PubMed 

    Google Scholar
     

  • Chen MW, Ye S, Zhao LL, Wang SY, Li YX, Yu CJ, et al. Association of plasma total and high-molecular-weight adiponectin with risk of colorectal cancer: an observational study in Chinese male. Med Oncol. 2012;29:3129–35.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Song M, Zhang X, Wu K, Ogino S, Fuchs CS, Giovannucci EL, et al. Plasma adiponectin and soluble leptin receptor and risk of colorectal cancer: a prospective study. Cancer Prev Res (Phila). 2013;6:875–85.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Aleksandrova K, Jenab M, Bueno-de-Mesquita HB, Fedirko V, Kaaks R, Lukanova A, et al. Biomarker patterns of inflammatory and metabolic pathways are associated with risk of colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Epidemiol. 2014;29:261–75.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Aleksandrova K, Drogan D, Boeing H, Jenab M, Bas Bueno-de-Mesquita H, Jansen E, et al. Adiposity, mediating biomarkers and risk of colon cancer in the European prospective investigation into cancer and nutrition study. Int J Cancer. 2014;134:612–21.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Abe Vicente M, Donizetti Silva T, Barão K, Vitor Felipe A, Oyama Missae L, Manoukian Forones N. The influence of nutritional status and disease on adiponectin and TNF-α; levels in colorectal cancer patients. Nutr Hosp. 2014;30:140–6.

    PubMed 

    Google Scholar
     

  • Erdogan S, Yilmaz FM, Yazici O, Yozgat A, Sezer S, Ozdemir N, et al. Inflammation and chemerin in colorectal cancer. Tumour Biol. 2016;37:6337–42.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chandler PD, Buring JE, Manson JE, Moorthy MV, Zhang S, Lee IM, et al. Association between plasma adiponectin levels and colorectal cancer risk in women. Cancer Causes Control. 2015;26:1047–52.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Inamura K, Song M, Jung S, Nishihara R, Yamauchi M, Lochhead P, et al. Prediagnosis plasma adiponectin in relation to colorectal cancer risk according to KRAS mutation status. J Natl Cancer Inst. 2016;108:djv363.

    Article 
    PubMed 

    Google Scholar
     

  • Florescu A, Branisteanu D, Bilha S, Scripcariu D, Florescu I, Scripcariu V, et al. Leptin and adiponectin dynamics at patients with rectal neoplasm—gender differences. PLoS One. 2019;14:e0212471.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhao X, Zhang Y, Deng L, Wang Y, Li Y, Chen M. The association between Chinese patients’ elevated omentin-1 levels, their clinicopathological features, and the risk of colorectal cancer. Int J Clin Exp Pathol. 2019;12:2264–74.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Polito R, Nigro E, Fei L, L DEM, Monaco ML, D’Amico R, et al. Adiponectin is inversely associated with tumour grade in colorectal cancer patients. Anticancer Res. 2020;40:3751–7.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Myte R, Harlid S, Sundkvist A, Gylling B, Häggström J, Zingmark C, et al. A longitudinal study of prediagnostic metabolic biomarkers and the risk of molecular subtypes of colorectal cancer. Sci Rep. 2020;10:5336.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mhaidat NM, Alzoubi KH, Kubas MA, Banihani MN, Hamdan N, Al-Jaberi TM. High levels of leptin and non-high molecular weight-adiponectin in patients with colorectal cancer: Association with chemotherapy and common genetic polymorphisms. Biomed Rep. 2021;14:13.

    CAS 
    PubMed 

    Google Scholar
     

  • Otake S, Takeda H, Suzuki Y, Fukui T, Watanabe S, Ishihama K, et al. Association of visceral fat accumulation and plasma adiponectin with colorectal adenoma: evidence for participation of insulin resistance. Clin Cancer Res. 2005;11:3642–6.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Fukumoto J, Otake T, Tajima O, Tabata S, Abe H, Mizoue T, et al. Adiponectin and colorectal adenomas: self defense forces health study. Cancer Sci. 2008;99:781–6.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Yamaji T, Iwasaki M, Sasazuki S, Tsugane S. Interaction between adiponectin and leptin influences the risk of colorectal adenoma. Cancer Res. 2010;70:5430–7.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Bobe G, Murphy G, Rogers CJ, Hance KW, Albert PS, Laiyemo AO, et al. Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention Trial. Cancer Epidemiol Biomarkers Prev. 2010;19:1441–52.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Chronis A, Thomopoulos K, Sapountzis A, Triantos C, Kalafateli M, Kalofonos C, et al. Adiposity factors are not related to the presence of colorectal adenomas. Clin Exp Gastroenterol. 2011;4:257–61.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • An W, Bai Y, Deng SX, Gao J, Ben QW, Cai QC, et al. Adiponectin levels in patients with colorectal cancer and adenoma: a meta-analysis. Eur J Cancer Prev. 2012;21:126–33.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wang Y, Li J, Fu X, Li J, Liu L, Alkohlani A, et al. Association of circulating leptin and adiponectin levels with colorectal cancer risk: a systematic review and meta-analysis of case-control studies. Cancer Epidemiol. 2021;73:101958.

    Article 
    PubMed 

    Google Scholar
     



  • Source link

    Related Articles

    Leave a Reply

    Stay Connected

    9FansLike
    4FollowersFollow
    0SubscribersSubscribe
    - Advertisement -spot_img

    Latest Articles

    %d bloggers like this: