Monday, May 29, 2023
BestWooCommerceThemeBuilttoBoostSales-728x90

Managing menopause: Hormone therapy is back


Credit: Pixabay/CC0 Public Domain

Hot flashes, night sweats and sleep disturbances are common symptoms of menopause that can affect health, quality of life and work productivity. A new review published in the Canadian Medical Association Journal (CMAJ ) recommends menopausal hormone therapy, historically known as hormone replacement therapy (HRT), as first-line treatment in people without risk factors.

Menopausal symptoms may occur up to 10 years before the last menstrual period and can last more than 10 years, with negative effects for many people.

“Menopause and perimenopause can be associated with distressing symptoms and reduced quality of life,” writes Dr. Iliana Lega, Women’s College Hospital and the University of Toronto, Toronto, Ontario, with co-authors. “Menopausal hormone therapy is the first-line treatment for vasomotor symptoms in the absence of contraindications.”

The review summarizes the latest evidence for diagnosing and treating menopausal symptoms as well as the risks and benefits of therapies to help clinicians and patients manage the condition.

“Although many treatments exist for , fears around the risks of and lack of knowledge regarding treatment options often impede patients from receiving treatment,” write the authors.

Benefits of menopausal hormone therapy include:

  • reduced in as many as 90% of patients with moderate to ;
  • improved blood lipid levels and a possible reduced risk of diabetes; and
  • fewer fragility fractures of the hip, spine and other bones.

What about the risks?

Although previous evidence has shown an increased risk of breast cancer, the risk is much lower in people aged 50–59 years and in those who start menopausal hormone therapy in the first 10 years of menopause. Some studies show an increased risk of ischemic stroke in women older than 60 years who start therapy 10 years after the start of menopause, but the risk is low for those younger than 60.

For people with risk factors or those who do not want to take menopausal hormone therapy, nonhormonal therapies, such as some (SSRIs) and other medications, can help alleviate symptoms.

“Despite early concerns of an increased risk of cardiovascular events with menopausal hormone therapy after the Women’s Health Initiative trial, increasing evidence shows a possible reduction in with menopausal hormone therapy among younger menopausal patients, specifically those who start menopausal hormone therapy before age 60 years or within 10 years of menopause,” write the authors.

They emphasize that it’s important for clinicians to ask about symptoms before and during menopause and to discuss treatments with patients based on their personal preferences and potential risk factors.

More information:
A pragmatic approach to the management of menopause, Canadian Medical Association Journal (2023). DOI: 10.1503/cmaj.221438

Citation:
Managing menopause: Hormone therapy is back (2023, May 15)
retrieved 15 May 2023
from https://medicalxpress.com/news/2023-05-menopause-hormone-therapy.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.





Source link

Related Articles

Leave a Reply

Stay Connected

9FansLike
4FollowersFollow
0SubscribersSubscribe
- Advertisement -spot_img

Latest Articles

%d bloggers like this: