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Phenylephrine: Commonly used decongestant in cold and flu remedies doesn’t work, says FDA


  1. Janice Hopkins Tanne
  1. New York

The US Food and Drug Administration (FDA) has reported that the decongestant phenylephrine, used in hundreds of over-the-counter cold, flu, and allergy remedies, does not work.123

The regulator’s independent Nonprescription Drugs Advisory Committee voted unanimously that “orally administered phenylephrine is not effective as a nasal decongestant at the monographed dosage (10 mg of phenylephrine hydrochloride every 4 hours) as well as at doses up to 40 mg (dosed every 4 hours).” The committee said that phenylephrine is still effective in nasal sprays and drops, which are less commonly used.

Phenylephrine …



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